Article
Genetic association between IL23R rs11209026 and rs10889677 polymorphisms and risk of Crohn's disease and ulcerative colitis: evidence from 41 studies.
Inflammation research : official journal of the European Histamine Research Society ... [et al.] - 1 Jan 2020
Zhu Yi, Jiang HongGang, Chen ZhiHeng, Lu BoHao, Li Jin, Shen XuNing
Abstract excerpt
OBJECTIVE: IL23R plays an important role in the pathogenesis of inflammatory bowel disease (IBD). The IL23R rs11209026 and rs10889677 polymorphisms have been shown to be associated with the development of Crohn's disease (CD) and ulcerative colitis (UC). But the results were inconsistent and inconclusive. So, we aim to investigate the genetic association between rs11209026 and rs10889677 polymorphisms and UC and...