rs1004819 is the main disease-associated IL23R variant in German Crohn's disease patients: combined analysis of IL23R, CARD15, and OCTN1/2 variants.

doi:10.1371/journal.pone.0000819

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Article

rs1004819 is the main disease-associated IL23R variant in German Crohn's disease patients: combined analysis of IL23R, CARD15, and OCTN1/2 variants.

PloS one - 5 Sept 2007

Glas Jürgen, Seiderer Julia, Wetzke Martin, Konrad Astrid, Török Helga-Paula, Schmechel Silke, Tonenchi Laurian, Grassl Christine, Dambacher Julia, Pfennig Simone, Maier Kerstin, Griga Thomas, Klein Wolfram, Epplen Jörg T, Schiemann Uwe, Folwaczny Christian, Lohse Peter, Göke Burkhard, Ochsenkühn Thomas, Müller-Myhsok Bertram, Folwaczny Matthias, Mussack Thomas, Brand Stephan

Abstract excerpt

BACKGROUND: The IL23R gene has been identified as a susceptibility gene for inflammatory bowel disease (IBD) in the North American population. The aim of our study was to test this association in a large German IBD cohort and to elucidate potential interactions with other IBD genes as well as phenotypic consequences of IL23R variants. METHODS: Genomic DNA from 2670 Caucasian individuals including 833 patients...

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Identifiers

PMID: 17786191
DOI: 10.1371/journal.pone.0000819
PMCID: PMC1950565

Genes

NOD2

Variants

rs11209026

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Source receipt: pubmed, retrieved 7 Sept 2026.

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