Article
Association of single nucleotide polymorphisms of IL23R and IL17 with ulcerative colitis risk in a Chinese Han population.
PloS one - 1 Jan 2012
Yu Pengli, Shen Fangcheng, Zhang Xiaofei, Cao Risheng, Zhao Xiaodan, Liu Pengfei, Tu Huiming, Yang Xiaozhong, Shi Ruihua, Zhang Hongjie
Abstract excerpt
BACKGROUND: Previous studies implicated that IL23R and IL17 genes play an important role in autoimmune inflammation. Genome-wide association studies have also identified multiple single nucleotide polymorphisms (SNPs) in the IL23R gene region associated with inflammatory bowel diseases. This study examined the association of IL23R and IL17A gene SNPs with ulcerative colitis susceptibility in a population in...
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