Article
Association of single nucleotide polymorphisms of IL23R and IL17 with ulcerative colitis risk in a Chinese Han population.
PloS one - 1 Jan 2012
Yu Pengli, Shen Fangcheng, Zhang Xiaofei, Cao Risheng, Zhao Xiaodan, Liu Pengfei, Tu Huiming, Yang Xiaozhong, Shi Ruihua, Zhang Hongjie
Abstract excerpt
BACKGROUND: Previous studies implicated that IL23R and IL17 genes play an important role in autoimmune inflammation. Genome-wide association studies have also identified multiple single nucleotide polymorphisms (SNPs) in the IL23R gene region associated with inflammatory bowel diseases. This stud...
Topics
- Adolescent
- Adult
- Aged
- Alleles
- Asian People
- Case-Control Studies
- China
- Colitis, Ulcerative
- Female
- Genetic Predisposition to Disease
- Genetic Variation
- Genotype
- Haplotypes
- Humans
- Interleukin-17
- Linkage Disequilibrium