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Article

IL23R haplotypes provide a large population attributable risk for Crohn's disease.

Inflammatory bowel diseases - 1 Sept 2008

Taylor Kent D, Targan Stephan R, Mei Ling, Ippoliti Andrew F, McGovern Dermot, Mengesha Emebet, King Lily, Rotter Jerome I

Abstract excerpt

BACKGROUND: The IL-23 pathway plays a pivotal role in the development of chronic mucosal inflammation seen in the inflammatory bowel diseases. Multiple studies have now established the contribution of the interleukin 23 receptor gene (IL23R) to Crohn's disease (CD) risk in general and of the IL23R R381Q variant in particular. The aim of this work was to estimate the total contribution of this gene to CD risk test...

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Identifiers

PMID: 18470928
DOI: 10.1002/ibd.20478
PMCID: PMC2574614

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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