Article
IL23R variation determines susceptibility but not disease phenotype in inflammatory bowel disease.
Gastroenterology - 1 May 2007
Tremelling Mark, Cummings Fraser, Fisher Sheila A, Mansfield John, Gwilliam Rhian, Keniry Andrew, Nimmo Elaine R, Drummond Hazel, Onnie Clive M, Prescott Natalie J, Sanderson Jeremy, Bredin Francesca, Berzuini Carlo, Forbes Alastair, Lewis Cathryn M, Cardon Lon, Deloukas Panos, Jewell Derek, Mathew Christopher G, Parkes Miles, Satsangi Jack
Abstract excerpt
BACKGROUND & AIMS: Identification of inflammatory bowel disease (IBD) susceptibility genes is key to understanding pathogenic mechanisms. Recently, the North American IBD Genetics Consortium provided compelling evidence for an association between ileal Crohn's disease (CD) and the IL23R gene usin...
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