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Article

Inferring the temporal order of cancer gene mutations in individual tumor samples.

PloS one - 1 Jan 2014

Guo Jun, Guo Hanliang, Wang Zhanyi

Abstract excerpt

The temporal order of cancer gene mutations in tumors is essential for understanding and treating the disease. Existing methods are unable to infer the order of mutations that are identified at the same time in individual tumor samples, leaving the heterogeneity of the order unknown. Here, we show that through a complex network-based approach, which is based on the newly defined statistic -carcinogenesis...

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PMID: 24586626
DOI: 10.1371/journal.pone.0089244
PMCID: PMC3937336

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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