Article

A Phylogenetic Approach to Inferring the Order in Which Mutations Arise during Cancer Progression

2020-05-08

Abstract excerpt

<h4> S ummary </h4> Although the role of evolutionary process in cancer progression is widely accepted, increasing attention is being given to the evolutionary mechanisms that can lead to differences in clinical outcome. Recent studies suggest that the temporal order in which somatic mutations accumulate during cancer progression is important. Single-cell sequencing provides a unique opportunity to examine the...

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Literature Corpus work: f1d28af1-dca2-56e5-96e0-225950d09be8
DOI: 10.1101/2020.05.06.081398

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