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Article

Inferring Sequential Order of Somatic Mutations during Tumorgenesis based on Markov Chain Model.

IEEE/ACM transactions on computational biology and bioinformatics - 1 Jan 2000

Kang Hao, Cho Kwang-Hyun, Zhang Xiaohua Douglas, Zeng Tao, Chen Luonan

Abstract excerpt

Tumors are developed and worsen with the accumulated mutations on DNA sequences during tumorigenesis. Identifying the temporal order of gene mutations in cancer initiation and development is a challenging topic. It not only provides a new insight into the study of tumorigenesis at the level of genome sequences but also is an effective tool for early diagnosis of tumors and preventive medicine. In this paper, we...

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Source

Identifiers

PMID: 26451822
DOI: 10.1109/TCBB.2015.2424408

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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