Article
DNA breathing dynamics distinguish binding from nonbinding consensus sites for transcription factor YY1 in cells.
Nucleic acids research - 1 Nov 2012
Alexandrov Boian S, Fukuyo Yayoi, Lange Martin, Horikoshi Nobuo, Gelev Vladimir, Rasmussen Kim Ø, Bishop Alan R, Usheva Anny
Abstract excerpt
The genome-wide mapping of the major gene expression regulators, the transcription factors (TFs) and their DNA binding sites, is of great importance for describing cellular behavior and phenotypic diversity. Presently, the methods for prediction of genomic TF binding produce a large number of fal...
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