Article
TFBSshape: an expanded motif database for DNA shape features of transcription factor binding sites.
Nucleic acids research - 8 Jan 2020
Chiu Tsu-Pei, Xin Beibei, Markarian Nicholas, Wang Yingfei, Rohs Remo
Abstract excerpt
TFBSshape (https://tfbsshape.usc.edu) is a motif database for analyzing structural profiles of transcription factor binding sites (TFBSs). The main rationale for this database is to be able to derive mechanistic insights in protein-DNA readout modes from sequencing data without available structures. We extended the quantity and dimensionality of TFBSshape, from mostly in vitro to in vivo binding and from...
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