Article
Highly-efficient, fluorescent, locus directed cre and FlpO deleter mice on a pure C57BL/6N genetic background.
Genesis (New York, N.Y. : 2000) - 1 Jun 2012
Birling Marie-Christine, Dierich Andrée, Jacquot Sylvie, Hérault Yann, Pavlovic Guillaume
Abstract excerpt
To facilitate the use of the new mutant resource developed in the mouse, we have generated Cre and FlpO deleter mice on a pure inbred C57BL/6N background. The new transgenic constructs were designed to drive either the Cre or FlpO recombinase, fused to a specific fluorescent marker, respectively the eGFP or the eYFP, and were inserted by homologous recombination in the neutral Rosa26 locus. They allow a rapid,...
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