Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Hippocampal GluA1-containing AMPA receptors mediate context-dependent sensitization to morphine.

The Journal of neuroscience : the official journal of the Society for Neuroscience - 9 Nov 2011

Xia Yan, Portugal George S, Fakira Amanda K, Melyan Zara, Neve Rachael, Lee H Thomas, Russo Scott J, Liu Jie, Morón Jose A

Abstract excerpt

Glutamatergic systems, including AMPA receptors (AMPARs), are involved in opiate-induced neuronal and behavioral plasticity, although the mechanisms underlying these effects are not fully understood. In the present study, we investigated the effects of repeated morphine administration on AMPAR expression, synaptic plasticity, and context-dependent behavioral sensitization to morphine. We found that morphine...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Disks Large Homolog 4 Protein
Share to Excitatory Postsynaptic Potentials

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Guanylate Kinases

Share to In Situ Nick-End Labeling

Share to Long-Term Potentiation

Share to Morphine

Share to Narcotics

Share to Receptors, AMPA

Source

Open in PubMed Open full text

Identifiers

PMID: 22072679
DOI: 10.1523/JNEUROSCI.3835-11.2011
PMCID: PMC3235051

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Hippocampal GluA1-containing AMPA receptors mediate context-dependent sensitization to morphine.PMID 22072679Read ↗

Phosphorylation of the AMPA receptor GluR1 subunit is required for synaptic plasticity and retention of spatial memory.Semantic proximity Read ↗

Ketamine blocks morphine-induced conditioned place preference and anxiety-like behaviors in miceSemantic proximity Read ↗

PKA phosphorylation of AMPA receptor subunits controls synaptic trafficking underlying plasticity.Semantic proximity Read ↗

Locomotor conditioning by amphetamine requires cyclin-dependent kinase 5 signaling in the nucleus accumbens.Semantic proximity Read ↗

Reversal of morphine-induced cell-type-specific synaptic plasticity in the nucleus accumbens shell blocks reinstatement.Semantic proximity Read ↗

Ketamine rescues anhedonia by cell-type and input specific adaptations in the Nucleus AccumbensSemantic proximity Read ↗

Phosphorylation of the AMPA receptor GluA1 subunit regulates memory load capacity.Semantic proximity Read ↗

Alterations in the emotional and memory behavioral phenotypes of transient receptor potential vanilloid type 1-deficient mice are mediated by changes in expression of 5-HT₁A, GABA(A), and NMDA receptors.Semantic proximity Read ↗

Knockout of ERK1 MAP kinase enhances synaptic plasticity in the striatum and facilitates striatal-mediated learning and memory.Semantic proximity Read ↗

Reversal of cocaine-evoked synaptic potentiation resets drug-induced adaptive behaviour.Semantic proximity Read ↗

Opiate sensitization induces FosB/ΔFosB expression in prefrontal cortical, striatal and amygdala brain regions.Semantic proximity Read ↗

Properties of contextual memory formed in the absence of αCaMKII autophosphorylation.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.