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Article

Opiate sensitization induces FosB/ΔFosB expression in prefrontal cortical, striatal and amygdala brain regions.

PloS one - 1 Jan 2011

Kaplan Gary B, Leite-Morris Kimberly A, Fan WenYing, Young Angela J, Guy Marsha D

Abstract excerpt

Sensitization to the effects of drugs of abuse and associated stimuli contributes to drug craving, compulsive drug use, and relapse in addiction. Repeated opiate exposure produces behavioral sensitization that is hypothesized to result from neural plasticity in specific limbic, striatal and cortical systems. ΔFosB and FosB are members of the Fos family of transcription factors that are implicated in neural...

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Identifiers

PMID: 21886798
DOI: 10.1371/journal.pone.0023574
PMCID: PMC3160315

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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