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Article

Properties of contextual memory formed in the absence of αCaMKII autophosphorylation.

Molecular brain - 28 Jan 2011

Irvine Elaine E, Danhiez Arthur, Radwanska Kasia, Nassim Charlotte, Lucchesi Walter, Godaux Emile, Ris Laurence, Giese K Peter

Abstract excerpt

The alpha-isoform of calcium/calmodulin-dependent kinase II (αCaMKII) is a major synaptic kinase that undergoes autophosphorylation after NMDA receptor activation, switching the kinase into a calcium-independent activity state. This αCaMKII autophosphorylation is essential for NMDA receptor-dependent long-term potentiation (LTP), induced by a single tetanus, in hippocampal area CA1 and in neocortex. Furthermore,...

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Identifiers

PMID: 21276220
DOI: 10.1186/1756-6606-4-8
PMCID: PMC3038913

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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