Article

Ketamine rescues anhedonia by cell-type and input specific adaptations in the Nucleus Accumbens

2023-06-09

Abstract excerpt

Ketamine’s role in providing a rapid and sustained antidepressant response, particularly for patients unresponsive to conventional treatments, is increasingly recognized. A core symptom of depression, anhedonia, or the loss of enjoyment or interest in previously pleasurable activities, is known to be significantly alleviated by ketamine. While several hypotheses have been proposed regarding the mechanisms by which...

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Literature Corpus work: 41f62498-a787-5ee0-91a1-98db7da04af5
DOI: 10.1101/2023.06.08.544088

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