Activation of K-ras by codon 13 mutations in C57BL/6 X C3H F1 mouse tumors induced by exposure to 1,3-butadiene.

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Article

Activation of K-ras by codon 13 mutations in C57BL/6 X C3H F1 mouse tumors induced by exposure to 1,3-butadiene.

Cancer research - 1 Aug 1990

Goodrow T, Reynolds S, Maronpot R, Anderson M

Abstract excerpt

1,3-Butadiene has been detected in urban air, gasoline vapors, and cigarette smoke. It has been estimated that 65,000 workers are exposed to this chemical in occupational settings in the United States. Lymphomas, lung, and liver tumors were induced in female and male C57BL/6 X C3H F1 (hereafter c...

Topics

Animals
Base Sequence
Blotting, Southern
Butadienes
Carcinogens
Cells, Cultured
Codon
DNA, Neoplasm
Gene Expression Regulation
Genes, ras
Liver Neoplasms, Experimental
Lung Neoplasms
Lymphoma
Mice
Mice, Inbred Strains
Molecular Sequence Data
Mutation
Oligonucleotide Probes

Source

Open in PubMed

Identifiers

PMID: 2196119

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026. Prepared record publication-2196119-2026-08-30.1. Manifest publication-graph-cohort-2026-08-30.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 30 Aug 2026.

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