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Article

H- and K-ras mutational profiles in chemically induced liver tumors from B6C3F1 and CD-1 mice.

Journal of toxicology and environmental health - 9 Feb 1996

Manjanatha M G, Li E E, Fu P P, Heflich R H

Abstract excerpt

Liver tumors from mice treated with genotoxic carcinogens often possess mutations in ras protooncogenes, and these sequence alterations in ras frequently reflect the mutational specificity of the carcinogen. Previous studies suggest that the mouse model used for tumor induction may affect ras mutational patterns. In order to explore this possibility, H- and K-ras mutational profiles were established in liver...

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PMID: 8598575
DOI: 10.1080/009841096161898

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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