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Article

Activation of protooncogenes in mouse lung tumors.

Experimental lung research - 1 Jan 2000

You M, Wang Y, Lineen A, Stoner G D, You L A, Maronpot R R, Anderson M W

Abstract excerpt

The detection of activated protooncogenes in mouse lung tumors has led to a major advance in our understanding of carcinogenesis of the lung at the molecular level. A high frequency of activated K-ras protooncogenes has been detected in tetranitromethane (TNM)- and 1,3-butadiene-induced lung tumors in B6C3F1 mice. In the past several years, we have pursued protooncogene activation in spontaneous and chemically...

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PMID: 2050038
DOI: 10.3109/01902149109064426

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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