Article
Further analysis of c-Ha-ras mutations in papillomas initiated by several polycyclic aromatic hydrocarbons and papillomas from uninitiated, promoter-treated skin in SENCAR mice.
Molecular carcinogenesis - 1 Jan 1993
DiGiovanni J, Beltrán L, Rupp A, Harvey R G, Gill R D
Abstract excerpt
In this study we analyzed the mutations in c-Ha-ras from skin papillomas initiated with benzo[a]pyrene (B[a]P), 7-methylbenz[a]anthracene (7-MBA), and 10-fluoro-7-methylbenz[a]anthracene (10-F-7-MBA) and from papillomas induced by treatment with tumor promoter alone. Among the papillomas induced...
Topics
- Animals
- Base Sequence
- Benz(a)Anthracenes
- Benzo(a)pyrene
- Carcinogens
- Codon
- DNA, Neoplasm
- Female
- Genes, ras
- Mice
- Mice, Inbred Strains
- Molecular Sequence Data
- Mutation
- Papilloma
- Polycyclic Compounds
- Skin
- Skin Neoplasms
- Skin Physiological Phenomena