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Article

Activation of cellular oncogenes by chemical carcinogens in Syrian hamster embryo fibroblasts.

Environmental health perspectives - 1 Aug 1990

Ebert R, Barrett J C, Wiseman R W, Pechan R, Reiss E, Röllich G, Schiffmann D

Abstract excerpt

Carcinogen-induced point mutations resulting in activation of ras oncogenes have been demonstrated in various experimental systems such as skin carcinogenesis, mammary, and liver carcinogenesis. In many cases, the data support the conclusion that these point mutations are critical changes in the initiation of these tumors. The Syrian hamster embryo (SHE) cell transformation model system has been widely used to...

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Source

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Identifiers

PMID: 2272311
DOI: 10.1289/ehp.9088175
PMCID: PMC1568019

Genes

SHE

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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