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Article

Innate immune defence: NOD2 and autophagy in the pathogenesis of Crohn's disease.

Swiss medical weekly - 1 Jan 2010

Hruz Petr, Eckmann Lars

Abstract excerpt

Crohn's disease (CD) is a chronic inflammatory disorder of the gut with a poorly understood aetiology. Epidemiological studies suggest that the disease occurs in genetically susceptible individuals as a consequence of defects in mucosal barrier function and disregulated immune recognition of commensal gut flora. Of more than 30 genetic loci associated with CD, two genes with important polymorphisms, encoding the...

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Source

Identifiers

PMID: 21213148
DOI: 10.4414/smw.2010.13135

Genes

NOD2

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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