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Article

NOD2 and bacterial recognition as therapeutic targets for Crohn's disease.

Expert opinion on therapeutic targets - 1 Dec 2017

de Bruyn Magali, Vermeire Séverine

Abstract excerpt

INTRODUCTION: Crohn's disease (CD) is a chronic, disabling disease of the gastrointestinal tract that mostly affects young adults. Despite extensive research, the pathogenesis of CD is still not completely understood. It is thought that an abnormal mucosal immune response is elicited towards the luminal microbiota in genetically predisposed persons. Genome-wide association studies and meta-analysis have greatly...

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Alleles
Autophagy
Crohn Disease
Gastrointestinal Microbiome
Genome-Wide Association Study

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Molecular Targeted Therapy

Nod2 Signaling Adaptor Protein

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Identifiers

PMID: 29096557
DOI: 10.1080/14728222.2017.1397627

Genes

NOD2

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 1 Sept 2026.

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