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Article

ATG16L1 and NOD2 interact in an autophagy-dependent antibacterial pathway implicated in Crohn's disease pathogenesis.

Gastroenterology - 1 Nov 2010

Homer Craig R, Richmond Amy L, Rebert Nancy A, Achkar Jean-Paul, McDonald Christine

Abstract excerpt

BACKGROUND & AIMS: The identification of numerous genes that confer susceptibility to Crohn's disease (CD) indicates that this complex disease might arise from alterations in several genes with related functions. We examined the functional interaction between the CD risk genes ATG16L1 and NOD2 to...

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Identifiers

PMID: 20637199
DOI: 10.1053/j.gastro.2010.07.006
PMCID: PMC2967588

Genes

NOD2

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-20637199-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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