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Article

Crohn's disease: a role of gut microbiota and Nod2 gene polymorphisms in disease pathogenesis.

Acta medica (Hradec Kralove) - 1 Jan 2014

Hrnčířová Lucia, Krejsek Jan, Šplíchal Igor, Hrnčíř Tomáš

Abstract excerpt

Crohn's disease is a chronic immune-mediated intestinal inflammation targeted against a yet incompletely defined subset of commensal gut microbiota and occurs on the background of a genetic predisposition under the influence of environmental factors. Genome-wide association studies have identified about 70 genetic risk loci associated with Crohn's disease. The greatest risk for Crohn's disease represent...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 25649363
DOI: 10.14712/18059694.2014.46

Genes

NOD2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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