Article
Abnormalities in the handling of intracellular bacteria in Crohn's disease: a link between infectious etiology and host genetic susceptibility.
Archivum immunologiae et therapiae experimentalis - 1 Jan 2000
Glasser Anne-Lise, Darfeuille-Michaud Arlette
Abstract excerpt
The etiology of Crohn's disease (CD) is still poorly understood, but recent advances have highlighted the importance of the innate immune system and the critical relationship between the gut flora and the intestinal mucosa. Several combinations of genetic factors predisposing to CD have been described, with the most significant replicable associations including genes for intracellular receptors of bacterial cell...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
