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Article

Evidence from genetics for a role of autophagy and innate immunity in IBD pathogenesis.

Digestive diseases (Basel, Switzerland) - 1 Jan 2012

Parkes Miles

Abstract excerpt

The early identification of NOD2 (nucleotide-binding oligomerization domain-containing protein 2) as a susceptibility gene for Crohn's disease first catalysed major interest in the role of innate immunity in IBD. This interest has been substantiated by genome-wide association studies with the identification of genetic association between Crohn's disease and variants in two separate autophagy genes, ATG16L1 and...

Read the complete abstract on PubMed

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 22796792
DOI: 10.1159/000338119

Genes

IRGM
NOD2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 3 Sept 2026.

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