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Article

Bacterial invasion: linking autophagy and innate immunity.

Current biology : CB - 9 Feb 2010

Galluzzi Lorenzo, Kepp Oliver, Zitvogel Laurence, Kroemer Guido

Abstract excerpt

Crohn's disease is a chronic inflammatory bowel disorder that has been associated with polymorphisms in the genes encoding the pattern-recognition receptor NOD2 and the autophagic regulator ATG16L1. A new study demonstrates that NOD2 recruits ATG16L1 at bacterial entry sites, thereby bridging innate immunity and autophagy.

Topics

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Autophagy
Autophagy-Related Proteins
Bacterial Infections
Carrier Proteins
Crohn Disease
Immunity, Innate

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Models, Biological

Nod2 Signaling Adaptor Protein

Source

Identifiers

PMID: 20144769
DOI: 10.1016/j.cub.2009.12.016

Genes

NOD2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 1 Sept 2026.

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Bacterial invasion: linking autophagy and innate immunity.PMID 20144769Read ↗

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