Article
Association of caspase-9 and RUNX3 with inflammatory bowel disease.
Tissue antigens - 1 Jan 2011
Guo C, Ahmad T, Beckly J, Cummings J R F, Hancock L, Geremia A, Cooney R, Pathan S, Jewell D P
Abstract excerpt
Previous linkage studies have identified a region at 1p36 as the susceptibility locus (IBD7) of inflammatory bowel disease (IBD). The objective of this study was to investigate whether polymorphisms of caspase-9 (CASP9) gene and RUNX3 are associated with IBD susceptibility and clinical phenotypes. We studied 555 Crohn's disease (CD) and 651 ulcerative colitis (UC) patients recruited from a single UK center. A...
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