Article

CARD9 in Neutrophils Protects from Colitis and Controls Mitochondrial Metabolism and Cell Survival

2022-01-15

Abstract excerpt

<h4>ABSTRACT</h4> <h4>Objectives</h4> Inflammatory bowel disease (IBD) results from a combination of genetic predisposition, dysbiosis of the gut microbiota and environmental factors, leading to alterations in the gastrointestinal immune response and chronic inflammation. Caspase recruitment domain 9 ( Card9 ), one of the IBD susceptibility genes, has been shown to protect against intestinal inflammation and fu...

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Literature Corpus work: c9acc3fe-bcf4-5cad-a3c2-7513663ed55d
DOI: 10.1101/2022.01.14.476327

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