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Article

Study of chromosomal region 5p13.1 in Crohn's disease, ulcerative colitis, and rheumatoid arthritis.

Human immunology - 1 Aug 2010

Perdigones Nieves, Martín Ezequiel, Robledo Gema, Lamas José Ramón, Taxonera Carlos, Díaz-Rubio Manuel, de la Concha Emilio G, López-Nevot Miguel Angel, García Antonio, Gómez-García María, Fernández-Gutiérrez Benjamín, Martín Javier, Urcelay Elena

Abstract excerpt

Chromosomal region 5p13 includes regulatory elements of the prostaglandin receptor EP4 (PTGER4) gene and is associated with inflammatory bowel disease (IBD) susceptibility. We aimed at corroborating the association of the PTGER4 risk variant in IBD. Given the proinflammatory activity of prostaglandin E(2) in rheumatoid arthritis (RA), the reduction in incidence and severity of collagen-induced arthritis observed...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 20561984
DOI: 10.1016/j.humimm.2010.05.010

Genes

PTGER4

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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