Article
Association between main Caspase gene polymorphisms and the susceptibility and prognosis of colorectal cancer.
Medical oncology (Northwood, London, England) - 1 Jan 2013
Wu Zhiwei, Li Ye, Li Shuying, Zhu Lin, Li Guangxiao, Yu Zhifu, Zhao Xiaojuan, Ge Jie, Cui Binbin, Dong Xinshu, Tian Suli, Hu Fulan, Zhao Yashuang
Abstract excerpt
Caspase (CASP) 3, 8, 9 are important caspases in the apoptosis pathway and play important roles in development and progression of cancer. A case-control study with 451 colorectal cancer (CRC) patients and 631 cancer-free controls were carried out, and CRC patients followed up, to investigate the associations between three main polymorphisms and colorectal cancer risk and prognosis, and their potential...
Topics
- Asian People
- Case-Control Studies
- Caspases
- Colorectal Neoplasms
- Female
- Genetic Predisposition to Disease
- Humans
- Male
- Middle Aged
- Polymorphism, Single Nucleotide