Article
Protective role of interleukin-19 gene polymorphisms in patients with ulcerative colitis.
Human immunology - 1 Nov 2011
Yamamoto-Furusho Jesús K, Álvarez-León Edith, Fragoso José Manuel, Gozalishvilli Anna, Vallejo Maite, Vargas-Alarcón Gilberto
Abstract excerpt
Ulcerative colitis (UC) is an inflammatory bowel disease (IBD) of unknown etiology. Interleukin (IL)-19 belongs to the IL-10 family and is a potent immunomodulatory cytokine, with implications for pathogenesis in IBD. No previous studies have reported this novel association between UC and IL-19 polymorphisms. In the present work, the role of IL-19 gene polymorphisms as susceptibility markers for UC was evaluated....
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