Article

Variants of the CASP9 gene as candidate markers for primary response to anti-TNF therapy in Crohn's disease patients

2023-08-16

Abstract excerpt

<title>Abstract</title> <p>Anti-tumor necrosis factor (TNF) therapy is used to induce and maintain remission in Crohn’s disease (CD) patients. However, primary non-responders to initial treatment constitute 20–40% of cases. The causes of this phenomenon are still unknown. We aim to investigate the impact of the caspase 9 (<italic>CASP9</italic>) gene variants on the variable reactions of CD patients to anti-TNF t...

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Literature Corpus work: 4dd69f74-3560-586a-9637-dff3c7e9d3df
DOI: 10.21203/rs.3.rs-3241807/v1

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