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Article

Runt-related transcription factor 3 is associated with ulcerative colitis and shows epistasis with solute carrier family 22, members 4 and 5.

Inflammatory bowel diseases - 1 Dec 2008

Weersma Rinse K, Zhou Lu, Nolte Ilja M, van der Steege Gerrit, van Dullemen Hendrik M, Oosterom Elvira, Bok Lisette, Peppelenbosch Maikel P, Faber Klaas N, Kleibeuker Jan H, Dijkstra Gerard

Abstract excerpt

BACKGROUND: Inflammatory bowel disease (IBD), comprising Crohn's disease (CD) and ulcerative colitis (UC), are intestinal inflammatory disorders with a complex genetic background. Mice deficient for the runt-domain-transcription-factor3 (Runx3) develop spontaneous colitis. Human RUNX3 resides in...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 18668679
DOI: 10.1002/ibd.20610

Genes

RUNX3

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-18668679-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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