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Article

Polymorphisms of caspase 8 and caspase 9 gene and colorectal cancer susceptibility and prognosis.

International journal of colorectal disease - 1 Sept 2011

Theodoropoulos George E, Gazouli Maria, Vaiopoulou Anna, Leandrou Myrto, Nikouli Sofia, Vassou Efthimia, Kouraklis Gregory, Nikiteas Nikolaos

Abstract excerpt

PURPOSE: Caspase-8 (CASP8) and caspase-9 (CASP9) play crucial roles in regulating apoptosis, and their functional polymorphisms may alter cancer risk. Our aim was to investigate the association between CASP8 and CASP9 gene polymorphisms and colorectal cancer (CRC) susceptibility. METHODS: A case-control study at 402 CRC patients and 480 healthy controls was undertaken in order to investigate the association...

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Identifiers

PMID: 21538054
DOI: 10.1007/s00384-011-1217-5

Genes

CASP9
CASP8

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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