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Article

Genetic variations in matrix metalloproteinases may be associated with increased risk of ulcerative colitis.

Human immunology - 1 Nov 2011

Morgan Angharad R, Han Dug-Yeo, Lam Wen-Jiun, Triggs Christopher M, Fraser Alan G, Barclay Murray, Gearry Richard B, Meisner Sander, Stokkers Pieter, Boeckxstaens Guy E, Ferguson Lynnette R

Abstract excerpt

Increased production of matrix metalloproteinases (MMPs) plays an important role in tissue damage in inflammatory bowel disease (IBD). Genetically encoded variation between individuals in MMP production may therefore contribute to disease onset, type, or severity. We undertook an extensive candidate gene single nucleotide polymorphism (SNP) study of MMP-1, -2, -3, -7, -8, -9, -10, -12, -13, and -14 and tissue...

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Identifiers

PMID: 21925226
DOI: 10.1016/j.humimm.2011.08.011

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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