Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Effects of BDNF Val66Met polymorphism on brain metabolism in Alzheimer's disease.

Neuroreport - 23 Aug 2010

Xu Cunlu, Wang Zhenhua, Fan Ming, Liu Bing, Song Ming, Zhen Xiantong, Jiang Tianzi

Abstract excerpt

Earlier studies showed that the Val66Met polymorphisms of the brain-derived neurotrophic factor differentially affect gray matter volume and brain region activities. This study used resting positron emission tomography to investigate the relationship between the polymorphisms of Val66Met and the regional cerebral metabolic rate in the brain. We analyzed the positron emission tomography images of 215 patients from...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Basal Metabolism
Share to Brain-Derived Neurotrophic Factor

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Brain Mapping

Share to Cognition Disorders

Share to Genetic Carrier Screening

Share to Methionine

Share to Positron-Emission Tomography

Share to Valine

Source

Open in PubMed Open full text

Identifiers

PMID: 20613678
DOI: 10.1097/WNR.0b013e32833ccaf4
PMCID: PMC2954459

Genes

BDNF

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Effects of BDNF Val66Met polymorphism on brain metabolism in Alzheimer's disease.PMID 20613678Read ↗

Effect of the BDNF Val66Met polymorphism on regional gray matter volumes and cognitive function in the Chinese population.Semantic proximity Read ↗

Effect of BDNF Val66Met on memory decline and hippocampal atrophy in prodromal Alzheimer's disease: a preliminary study.Semantic proximity Read ↗

Effect of BDNF Val66Met polymorphism on regional white matter hyperintensities and cognitive function in elderly males without dementia.Semantic proximity Read ↗

Association of the brain-derived neurotrophic factor val66met polymorphism with magnetic resonance spectroscopic markers in the human hippocampus: in vivo evidence for effects on the glutamate system.Semantic proximity Read ↗

Dosage effects of BDNF Val66Met polymorphism on cortical surface area and functional connectivity.Semantic proximity Read ↗

Brain-derived neurotrophic factor val66met polymorphism affects prefrontal energy metabolism in bipolar disorder.Semantic proximity Read ↗

Brain-derived neurotrophic factor (BDNF) Val(66)Met polymorphism differentially predicts hippocampal function in medication-free patients with schizophrenia.Semantic proximity Read ↗

Met carriers of the BDNF Val66Met polymorphism show reduced Glx/NAA in the pregenual ACC in two independent cohorts.Semantic proximity Read ↗

The impact of brain-derived neurotrophic factor Val66Met polymorphism on cognition and functional brain networks in patients with intractable partial epilepsy.Semantic proximity Read ↗

The brain-derived neurotrophic factor VAL66MET polymorphism and cerebral white matter hyperintensities in late-life depression.Semantic proximity Read ↗

Dose-dependent effect of the Val66Met polymorphism of the brain-derived neurotrophic factor gene on memory-related hippocampal activity.Semantic proximity Read ↗

BDNF Val66Met, Aβ amyloid, and cognitive decline in preclinical Alzheimer's disease.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.