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Article

Dosage effects of BDNF Val66Met polymorphism on cortical surface area and functional connectivity.

The Journal of neuroscience : the official journal of the Society for Neuroscience - 12 Feb 2014

Wang Chao, Zhang Yuanchao, Liu Bing, Long Haixia, Yu Chunshui, Jiang Tianzi

Abstract excerpt

The single nucleotide polymorphism (SNP) that leads to a valine-to-methionine substitution at codon 66 (Val66Met) in BDNF is correlated with differences in cognitive and memory functions, as well as with several neurological and psychiatric disorders. MRI studies have already shown that this genetic variant contributes to changes in cortical thickness and volume, but whether the Val66Met polymorphism affects the...

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Identifiers

PMID: 24523553
DOI: 10.1523/JNEUROSCI.3501-13.2014
PMCID: PMC6802754

Genes

BDNF

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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