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Article

Effect of BDNF Val66Met polymorphism on regional white matter hyperintensities and cognitive function in elderly males without dementia.

Psychoneuroendocrinology - 1 Jan 2014

Huang Chu-Chung, Liu Mu-En, Chou Kun-Hsien, Yang Albert C, Hung Chia-Chun, Hong Chen-Jee, Tsai Shih-Jen, Lin Ching-Po

Abstract excerpt

White matter lesions, also termed White Matter Hyperintensities (WMH), on T2-weighted MR images, are common in the elderly population. Of note, their presence is often accompanied with cognitive decline and the risk of dementia. Even though previous brain ischemia and WM lesion studies have been conducted and indicated that brain-derived neurotrophic factor (BDNF) might protect against neuronal cell death, the...

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Identifiers

PMID: 24275008
DOI: 10.1016/j.psyneuen.2013.09.027

Genes

BDNF

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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