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Article

The Smc5/6 complex is required for dissolution of DNA-mediated sister chromatid linkages.

Nucleic acids research - 1 Oct 2010

Bermúdez-López Marcelino, Ceschia Audrey, de Piccoli Giacomo, Colomina Neus, Pasero Philippe, Aragón Luis, Torres-Rosell Jordi

Abstract excerpt

Mitotic chromosome segregation requires the removal of physical connections between sister chromatids. In addition to cohesin and topological entrapments, sister chromatid separation can be prevented by the presence of chromosome junctions or ongoing DNA replication. We will collectively refer to them as DNA-mediated linkages. Although this type of structures has been documented in different DNA replication and...

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Identifiers

PMID: 20571088
DOI: 10.1093/nar/gkq546
PMCID: PMC2965248

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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