Article
Smc5p promotes faithful chromosome transmission and DNA repair in Saccharomyces cerevisiae.
Genetics - 1 Apr 2006
Cost Gregory J, Cozzarelli Nicholas R
Abstract excerpt
Heterodimers of structural maintenance of chromosomes (SMC) proteins form the core of several protein complexes involved in the organization of DNA, including condensation and cohesion of the chromosomes at metaphase. The functions of the complexes with a heterodimer of Smc5p and Smc6p are less clear. To better understand them, we created two S. cerevisiae strains bearing temperature-sensitive alleles of SMC5....
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