Article
H2A.Z-dependent regulation of cohesin dynamics on chromosome arms.
Molecular and cellular biology - 1 Jun 2014
Tapia-Alveal Claudia, Lin Su-Jiun, Yeoh Aaron, Jabado Omar J, O'Connell Matthew J
Abstract excerpt
Structural maintenance of chromosomes (SMC) complexes and DNA topoisomerases are major determinants of chromosome structure and dynamics. The cohesin complex embraces sister chromatids throughout interphase, but during mitosis most cohesin is stripped from chromosome arms by early prophase, while the remaining cohesin at kinetochores is cleaved at anaphase. This two-step removal of cohesin is required for sister...
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