Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

SMC complexes and topoisomerase II work together so that sister chromatids can work apart.

Cell cycle (Georgetown, Tex.) - 1 Jun 2010

Tapia-Alveal Claudia, Outwin Emily A, Trempolec Natalia, Dziadkowiec Dorota, Murray Johanne M, O'Connell Matthew J

Abstract excerpt

The pairing of sister chromatids in interphase facilitates error-free homologous recombination (HR). Sister chromatids are held together by cohesin, one of three Structural Maintenance of Chromosomes (SMC) complexes. In mitosis, chromosome condensation is controlled by another SMC complex, condensin, and the type II topoisomerase (Top2). In prophase, cohesin is stripped from chromosome arms, but remains at...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Chromatids
Share to Chromosomal Proteins, Non-Histone

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Chromosome Segregation

Share to Cohesins

Share to DNA Topoisomerases, Type II

Share to Genomic Instability

Share to Schizosaccharomyces

Share to Schizosaccharomyces pombe Proteins

Source

Identifiers

PMID: 20495382
DOI: 10.4161/cc.9.11.11734

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

SMC complexes and topoisomerase II work together so that sister chromatids can work apart.PMID 20495382Read ↗

H2A.Z-dependent regulation of cohesin dynamics on chromosome arms.Semantic proximity Read ↗

The Smc5/6 complex is required for dissolution of DNA-mediated sister chromatid linkages.Semantic proximity Read ↗

Faithful anaphase is ensured by Mis4, a sister chromatid cohesion molecule required in S phase and not destroyed in G1 phase.Semantic proximity Read ↗

SMC5 and MMS21 are required for chromosome cohesion and mitotic progression.Semantic proximity Read ↗

Smc5/6 is required for repair at collapsed replication forks.Semantic proximity Read ↗

Cohesins: chromosomal proteins that prevent premature separation of sister chromatids.Semantic proximity Read ↗

Specialized interfaces of Smc5/6 control hinge stability and DNA association.Semantic proximity Read ↗

Cohesin-mediated DNA loop extrusion resolves sister chromatids in G2 phaseSemantic proximity Read ↗

A role for Drosophila SMC4 in the resolution of sister chromatids in mitosis.Semantic proximity Read ↗

SMC2, a Saccharomyces cerevisiae gene essential for chromosome segregation and condensation, defines a subgroup within the SMC family.Semantic proximity Read ↗

SMC1B is present in mammalian somatic cells and interacts with mitotic cohesin proteins.Semantic proximity Read ↗

Cdc14 phosphatase induces rDNA condensation and resolves cohesin-independent cohesion during budding yeast anaphase.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.