Article
Pds5p regulates the maintenance of sister chromatid cohesion and is sumoylated to promote the dissolution of cohesion.
The Journal of cell biology - 24 Nov 2003
Stead Kristen, Aguilar Cristina, Hartman Theresa, Drexel Melissa, Meluh Pamela, Guacci Vincent
Abstract excerpt
Pds5p and the cohesin complex are required for sister chromatid cohesion and localize to the same chromosomal loci over the same cell cycle window. However, Pds5p and the cohesin complex likely have distinct roles in cohesion. We report that pds5 mutants establish cohesion, but during mitosis exh...
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