Article
Expression of Bv8 in Pichia pastoris to identify structural features for receptor binding.
Protein expression and purification - 1 Sept 2010
Miele Rossella, Lattanzi Roberta, Bonaccorsi di Patti Maria Carmela, Paiardini Alessandro, Negri Lucia, Barra Donatella
Abstract excerpt
Bv8 is an amphibian peptide belonging to the widely distributed AVIT protein family. The mammalian orthologues of Bv8 were named prokineticin 1 and prokineticin 2. Two G-protein-coupled receptors for Bv8-prokineticins have been identified. The biological activities of Bv8/PK proteins range from angiogenesis and involvement in reproduction and cancer, to neuronal survival and neurogenesis, hypothalamic hormone...
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