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Article

Functional role of the intracellular loop linking transmembrane domains 6 and 7 of the human dipeptide transporter hPEPT1.

The Journal of membrane biology - 1 Dec 2010

Xu Liya, Li Yiyu, Haworth Ian S, Davies Daryl L

Abstract excerpt

The human intestinal di-/tripeptide transporter (hPEPT1) is a 12-transmembrane protein that facilitates transport of peptides from the intestine into the circulation. hPEPT1 is also an important target in oral delivery of drugs, but mechanistic and structural data for the protein are limited. In particular, there is little information on the function of the loops of the transporter. In this study, we show that...

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Identifiers

PMID: 21104182
DOI: 10.1007/s00232-010-9317-7
PMCID: PMC3032433

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

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