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Article

Agonist-dependent phosphorylation of the formyl peptide receptor is regulated by the membrane proximal region of the cytoplasmic tail.

Biochimica et biophysica acta - 1 Feb 2009

Suvorova Elena S, Gripentrog Jeannie M, Jesaitis Algirdas J, Miettinen Heini M

Abstract excerpt

Formyl peptide receptor (FPR) is a chemoattractant G protein-coupled receptor (GPCR) involved in the innate immune response against bacteria. Receptor activation is terminated by receptor phosphorylation of two serine- and threonine-rich regions located in the distal half of the cytoplasmic tail. In this study we show that introduction of an amino acid with a bulky side chain (leucine or glutamine) adjacent to a...

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Identifiers

PMID: 18952127
DOI: 10.1016/j.bbamcr.2008.09.011
PMCID: PMC2709459

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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