Article
Residue-specific bioincorporation of non-natural, biologically active amino acids into proteins as possible drug carriers: structure and stability of the per-thiaproline mutant of annexin V.
Proceedings of the National Academy of Sciences of the United States of America - 20 Jan 1998
Budisa N, Minks C, Medrano F J, Lutz J, Huber R, Moroder L
Abstract excerpt
Residue-specific bioincorporation of 1,3-thiazolidine-4-carboxylic acid [thiaproline, Pro(S)], a non-natural amino acid analog of proline, into human recombinant annexin V was achieved with a proline-auxotrophic Escherichia coli strain by fermentation procedures in minimal medium. Quantitative re...
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