Article
Role of transmembrane domains in the functions of B- and T-cell receptors.
Immunology letters - 1 Dec 1998
Zidovetzki R, Rost B, Pecht I
Abstract excerpt
The antigen receptors on the surface of B- and T-lymphocytes are complexes of several integral membrane proteins, essential for their proper expression and function. Recent studies demonstrated that transmembrane (TM) domains of the components of these receptors play a critical role in their association and function. It was specifically demonstrated that in many cases point mutations in the TM domains can...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.