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Article

Molecular requirements for the insecticidal activity of the plant peptide pea albumin 1 subunit b (PA1b).

The Journal of biological chemistry - 22 Oct 2010

Da Silva Pedro, Rahioui Isabelle, Laugier Christian, Jouvensal Laurence, Meudal Hervé, Chouabe Christophe, Delmas Agnès F, Gressent Frédéric

Abstract excerpt

PA1b (pea albumin 1, subunit b) is a small and compact 37-amino acid protein, isolated from pea seeds (Pisum sativum), that adopts a cystine knot fold. It acts as a potent insecticidal agent against major pests in stored crops and vegetables, making it a promising bioinsecticide. Here, we investigate the influence of individual residues on the structure and bioactivity of PA1b. A collection of 13 PA1b mutants was...

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Identifiers

PMID: 20660598
DOI: 10.1074/jbc.M110.147199
PMCID: PMC2963353

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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